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CC, a 72 year old female, complains to the pharmacist that her stomach has been bothering her recently. Current medications include: levothyroxine 0.1 mg po daily (x 30 years), acetaminophen 500 mg po qid (x 5 months), atorvastatin 40 mg po hs (x 4 years), ibuprofen 400 mg po tid prn for joint pain (x 2 months) and zopiclone 3.75 mg po hs prn (x 3 months). Which of the following drug therapy problems is most likely contributing to CC’s recent symptoms?

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Use of ibuprofen without gastroprotection

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